Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by upper and lower motor neuron degeneration. Degeneration of upper motor neurons occurs in the corticospinal tract and lower motor neurons occurs in the plexuses that innervate the skeletal muscles. Patients experience systemic muscle weakness, dysphagia, and spasticity that ultimately results in respiratory failure. […]
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