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Glutamate and GABA Neurotransmission in Autism

The Synaptic Symphony in Balance Unraveling the Neurotransmitter Scales of Autism Spectrum Disorder “This literature review summarizes recent postmortem, genetic, and neurophysiological findings to provide a multi-scale mechanistic exploration of how the imbalance between excitatory glutamatergic drive and inhibitory GABAergic…

Clinical Spectrum of Multiple Sclerosis

The Smoldering Fire: A Systematic Review of the Literature on the Clinical Spectrum, Neurobiological Mechanisms and Therapeutic Development in Transition from Relapsing to Progressive Multiple Sclerosis “This comprehensive review describes the continuum of clinical and pathologic features of multiple sclerosis…

mtDNA Mutations and ROS-Induced Hearing Loss

The Silent Powerhouses: Mutations in Mitochondrial DNA and Excessive Production of Reactive Oxygen Species Silence the Outer Hair Cells in Hearing Loss “This review reveals the silent crisis within the inner ear, showing how unprotected mitochondrial DNA mutations and disastrous…

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