Introduction Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms (tremor, rigidity, bradykinesia) and non-motor or premotor symptoms (NMS) such as depression, anxiety, sleep disturbances, and cognitive decline. These non-motor manifestations often appear years before classical motor signs, indicating a prolonged prodromal phase of neurodegeneration. Recent advances in regenerative medicine highlight Mesenchymal Stem Cell (MSC) therapy as a […]
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Clinical Utility of MSC Stem Cell in Regenerative Medicine Overview of MSC Stem Cell Mesenchymal stem/stromal cells (MSCs) are multipotent somatic stem cells capable of self-renewal, multilineage differentiation, and strong immunomodulation. They can be derived from multiple sources such as bone marrow, adipose tissue, umbilical cord, placenta, amniotic fluid, cord blood, and dental pulp. Their […]
Chronic lung diseases such as Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Fibrosis, and Post-COVID lung damage remain among the most challenging conditions to treat. Traditional therapies focus on symptom relief, oxygen management, and slowing disease progression, but they rarely repair the underlying tissue damage. In recent years, umbilical cord-derived mesenchymal stem cells (UC-MSCs) have emerged as a promising option for lung regeneration […]
In recent years, the understanding of autism spectrum disorder (ASD) has shifted from focusing solely on behavior to exploring underlying biological and neurological factors. This progress has opened new possibilities in regenerative medicine, especially through umbilical cord-derived stem cell therapy. In Thailand, known for its excellence in regenerative health and international-standard medical care, stem cell therapy for autism is emerging as a […]
Diabetes mellitus, especially type 2 diabetes (T2D), is a chronic metabolic condition marked by insulin resistance, impaired insulin secretion, and long-term complications affecting the cardiovascular system, kidneys, nerves, and eyes. Despite the availability of medications and insulin therapy, conventional treatment often falls short of reversing disease progression. In recent years, umbilical cord-derived mesenchymal stem cells (UC-MSC stem cells) have emerged as […]
Scope & Rationale Research on Autism (ASD) increasingly explores stem cell approaches especially mesenchymal stem cells (MSCs)—for their immunomodulatory, anti-inflammatory, and paracrine actions that may influence behavior, sleep, social interaction, and gastrointestinal symptoms. Current stem cell evidence in Autism is promising but heterogeneous, and it does not yet establish causality or a universal protocol. Clinical Evidence (high level) Randomized / Controlled Studies Trials comparing intrathecal bone-marrow MSC stem cell therapy […]
Chronic back pain is one of the most common and disabling health conditions worldwide, affecting people across all ages and lifestyles. Conventional treatments for chronic back pain typically include physical rehabilitation, oral medications, steroid injections, or surgical intervention. While these options can be helpful, they often focus on managing symptoms rather than repairing the damaged […]
Bone fractures are among the most common injuries treated in modern medicine. They can occur due to traumatic accidents, repetitive physical stress, sports injuries, or medical conditions that weaken skeletal strength, such as osteoporosis. In many cases, the human body is capable of repairing fractured bones through a natural healing process that unfolds in stages—initial […]
As people live longer than ever before, the focus of aging has shifted from simply extending lifespan to preserving health, energy, and quality of life. Many individuals want to remain physically active, mentally sharp, and confident in their appearance well into later years. Conventional anti-aging approaches can offer short-term or surface-level improvements, but they do […]
Female infertility has become an increasingly significant health concern worldwide, affecting countless women and couples who hope to conceive. Medically, infertility is defined as the inability to achieve pregnancy after at least one year of consistent, unprotected intercourse. Beyond its clinical definition, infertility often brings emotional stress, uncertainty, and complex treatment decisions. A variety of […]
Advances in regenerative medicine continue to push the boundaries of how the body can heal itself. One of the most exciting frontiers is the combined use of umbilical cord-derived mesenchymal stem cells (UC-MSC stem cells) and natural killer (NK) cells, which harness both regenerative and immune-enhancing properties. This powerful therapeutic duo is gaining attention for its ability to […]
As women age, their ovarian function naturally declines, leading to reduced fertility, hormonal imbalance, and the onset of perimenopause or menopause. In recent years, ovarian rejuvenation with stem cell therapy has emerged as an innovative and promising solution to help women restore ovarian function, improve egg quality, and potentially enhance fertility even in cases of low ovarian […]
Disc bulge, spinal degeneration, and hip joint deterioration are common age-related or injury-induced conditions that can severely affect mobility and quality of life. Traditional medical advice often points directly to surgical solutions, such as spinal fusion or total hip replacement, even when patients do not yet feel significant pain. However, Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSC Stem Cells) are emerging […]
Ovarian aging is one of the most significant factors affecting female fertility. As women age, the number and quality of eggs naturally decline, leading to reduced ovarian reserve, hormonal imbalance, and in many cases, infertility. Traditional solutions such as hormone replacement therapy (HRT) and in vitro fertilization (IVF) can help, but they do not restore […]
Knee osteoarthritis (OA) is a degenerative joint disease that significantly affects the quality of life in millions of people worldwide. Characterised by the progressive deterioration of articular cartilage, chronic inflammation, and joint stiffness, knee OA leads to pain, reduced mobility, and, ultimately, disability in advanced stages. Traditional treatment options such as pain medications, physical therapy, hyaluronic […]
Osteoporosis is a chronic condition that causes bones to become weak, brittle, and more likely to break. It occurs when the body loses too much bone, makes too little, or both disrupting the natural balance of bone remodeling. While current treatments like calcium supplements, medications, and lifestyle changes can help slow this process, they typically […]
Chronic back pain is among the most common causes of long-term disability worldwide, affecting individuals of all ages and activity levels. For many patients, finding a treatment that offers lasting relief rather than temporary symptom suppression remains a significant challenge. Conventional back pain treatments typically focus on controlling pain rather than repairing the damaged tissues […]
Type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic metabolic diseases worldwide, with incidence rates continuing to climb each year. The condition develops through a combination of insulin resistance—where the body’s cells no longer respond effectively to insulin—and the gradual decline of insulin production by pancreatic beta cells. Over time, this dual […]
Bone fractures are among the most common injuries treated in orthopedic medicine. In many cases, the body is capable of repairing fractured bone through a highly coordinated biological process involving inflammation, cell recruitment, and tissue remodeling. However, this natural healing sequence does not always proceed as expected. Severe trauma, large bone defects, poor bone quality, […]
Type 1 diabetes is a lifelong autoimmune disorder characterized by the destruction of insulin-producing beta (β) cells within the pancreas. These specialized cells, found in clusters known as pancreatic islets, are essential for maintaining balanced blood glucose levels. In individuals with Type 1 diabetes, the immune system mistakenly identifies these cells as threats and gradually […]