Autism and stem cell therapy

What is the treatment with stem cells?

Different sorts of cells, including brain, blood, heart, skin, and stem cells, make up our body. Numerous different cell types can be produced from stem cells.

In stem cell therapy, damaged cells are repaired or replaced by injecting stem cells into the autism patient to treat a variety of ailments. Either the autism patient or a donor may provide the stem cells. Conditions like burns, blood malignancies, and corneal damage are treated using stem cell therapy.

 

What uses does stem cell therapy serve for Autism?

Proponents of stem cell treatment for autism claim that it can lessen the symptoms of autism. It is said to help with focus, conduct, anxiety, social skills, speech, and communication.

 

What is the theory behind stem cell treatment for individuals with autism?

Stem cells have been demonstrated to have anti-inflammatory and immune-boosting properties in specific diseases, such as leukaemia.

Advocates of stem cell treatment for autism assert that immune system issues and inflammation are linked to autism. It is said that a person with autism will exhibit less traits if they receive stem cell injections.

 

What is involved in stem cell therapy for individuals with autism?

However, the course of treatment often entails the following phases:

  1. Pre-treatment evaluations: in order to determine whether a autism patient is eligible for therapy, the autism patient may undergo physical examinations, blood tests, and reviews of their medical history prior to beginning treatment.
  2. Collection: Different types of stem cells are obtained, and their preparation and collection methods differ. For instance, bone marrow, umbilical cords, and donor placentas can all be used to harvest stem cells. Additionally, they can be taken straight from the patient’s fat, cerebrospinal fluid, or bone marrow. This might hurt and be intrusive.
  3. Cultivation: Some stem cells may require a few weeks of laboratory growth following collecting.
  4. Injection: The autism patient’s vein is used to inject the cells. This might hurt and be intrusive. It is possible that the patient will require an anaesthetic and/or hospital admission. A patient may have several stem cell injections over the course of a few days, weeks, or months, depending on the facility.
  5. Follow-up: Following each treatment, follow-up appointments are typically scheduled.

 

What role does autism play?

The much more prevalent disorder of autism has been treated with stem cells thanks to the success of stem cell therapy for cerebral palsy. Cerebral palsy and autism are neurodevelopmental illnesses, yet they differ greatly from one another. ​​Given the evidence that some types of stem cells administered intravenously can enhance both the brain’s neuronal connectivity and the immune system’s general control, stem cell therapy for autism is a promising treatment option. However, research on autism is not progressing as quickly as that on cerebral palsy. There were 70 stem cell clinical studies for cerebral palsy and other closely related disorders conducted globally between 2011 and 2018, compared to just 14 trials for autism.

 

Why treat autism with Mesenchymal Stem Cells (MSC)?

According to the most recent immunology studies, MSC are not immune privileged in the fullest sense; rather, it would be more correct to describe them as “immune evasive”.  Extensive study indicates that many individuals do acquire anti-bodies against the donor following MSC reception. Thankfully, these anti-bodies are present at a very low concentration that does not result in symptoms, however it is yet unclear how long they will last. In general, MSC exhibit exceptional safety records. In the last 10 years, tens of thousands of autism patients have benefited from MSC injections or infusions from unrelated donors without encountering a graft versus host reaction.