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Therapeutic Applications of Cord-Derived Mesenchymal Stem Cells in Systemic Lupus Erythematosus Integrated with Double-Filtration Plasmapheresis: Mechanisms, Evidence and Clinical Pilot

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by systemic inflammation and immunological dysfunction resulting in robust autoantibody production. Even with significant improvement over the past few decades, some patients remain refractory to conventional therapy, this is simply…

Stem Cell Therapy Using UC-MSCs Combined with Double-Filtration Plasmapheresis in Amyotrophic Lateral Sclerosis: A Review of Mechanisms, Evidence, and Clinical Considerations

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease characterized by the selective loss of motor neurons, leading to muscle weakness, paralysis, and eventual respiratory failure. Current therapies provide limited disease-modifying effects, prompting increasing interest in regenerative approaches. Among these, umbilical…

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